Version 5.4
Homo sapiens Gene: HMGN5
Summary
InnateDB Gene IDBG-78260.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HMGN5
Gene Name high mobility group nucleosome binding domain 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198157
Encoded Proteins
IDBP-78262
high mobility group nucleosome binding domain 5
IDBP-78266
high mobility group nucleosome binding domain 5
IDBP-376838
high mobility group nucleosome binding domain 5
IDBP-376841
high mobility group nucleosome binding domain 5
IDBP-376845
high mobility group nucleosome binding domain 5
IDBP-376848
high mobility group nucleosome binding domain 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:81113701-81201942
Strand Reverse strand
Band q21.1
Transcripts
ENST00000358130 ENSP00000350848
ENST00000373250 ENSP00000362347
ENST00000447319 ENSP00000408060
ENST00000430960 ENSP00000399626
ENST00000436386 ENSP00000413402
ENST00000451455 ENSP00000404810
ENST00000491275
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0031492 nucleosomal DNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0016568 chromatin modification
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031245
View Gene Order
ENSBTAG00000001877
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.282204
RefSeq NM_030763 XM_006724688 XM_006724689 XM_006724690
HUGO
OMIM
CCDS CCDS14448
HPRD 02310
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca