Version 5.4
Homo sapiens Gene: C6orf25
Summary
InnateDB Gene IDBG-78777.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C6orf25
Gene Name chromosome 6 open reading frame 25
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000204420
Encoded Proteins
IDBP-78779
chromosome 6 open reading frame 25
IDBP-78783
chromosome 6 open reading frame 25
IDBP-78785
chromosome 6 open reading frame 25
IDBP-78787
chromosome 6 open reading frame 25
IDBP-78789
chromosome 6 open reading frame 25
IDBP-78791
chromosome 6 open reading frame 25
IDBP-473748
chromosome 6 open reading frame 25
IDBP-480076
chromosome 6 open reading frame 25
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:31718594-31726714
Strand Forward strand
Band p21.33
Transcripts
ENST00000375810 ENSP00000364968
ENST00000375809 ENSP00000364967
ENST00000375814 ENSP00000364972
ENST00000375806 ENSP00000364964
ENST00000375805 ENSP00000364963
ENST00000375804 ENSP00000364962
ENST00000460663
ENST00000480039 ENSP00000419306
ENST00000485548 ENSP00000420355
ENST00000466312
ENST00000471545
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008201 heparin binding
Biological Process
GO:0007229 integrin-mediated signaling pathway
GO:0007596 blood coagulation
GO:0030220 platelet formation
GO:0035855 megakaryocyte development
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000073414
View Gene Order
ENSBTAG00000013525
Not yet available
Cross-References
SwissProt O95866
TrEMBL
UniProt Splice Variant
Entrez Gene 80739
UniGene Hs.247879
RefSeq NM_138275 NM_025260 NM_138272 NM_138273 NM_138274 NM_138277
HUGO HGNC:13937
OMIM 606520
CCDS CCDS34405 CCDS34406 CCDS34407 CCDS4715 CCDS4716 CCDS4717
HPRD 09405
IMGT
EMBL AF129756 AJ292259 AJ292260 AJ292261 AJ292262 AJ292263 AJ292264 AJ292265 AL662899 AL670886 AL844216 BA000025 BC113719 BC113721 BX248244 CH471081 CR354443 CR759787 CR936239
GenPept AAD18075 AAI13720 AAI13722 BAB63378 CAC83496 CAC83497 CAC83498 CAC83499 CAC83500 CAC83501 CAC83502 CAI17813 CAI17814 CAI17815 CAI17816 CAI17818 CAI18406 CAI18407 CAI18408 CAI18409 CAI18412 CAM26092 CAM26093 CAM26094 CAM26095 CAM26096 CAM45767 CAM45768 CAM45769 CAM45770 CAM45771 CAQ07017 CAQ07020 CAQ07021 CAQ08890 CAQ08892 CAQ08893 CAQ08894 CAQ10105 CAQ10107 CAQ10108 CAQ10109 EAX03493 EAX03494 EAX03497 EAX03498
RNA Seq Atlas 80739

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca