Version 5.4
Homo sapiens Gene: ANO7
Summary
InnateDB Gene IDBG-85069.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANO7
Gene Name anoctamin 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146205
Encoded Proteins
IDBP-85071
anoctamin 7
IDBP-295650
anoctamin 7
IDBP-295335
anoctamin 7
IDBP-389640
anoctamin 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:241188509-241225377
Strand Forward strand
Band q37.3
Transcripts
ENST00000274979 ENSP00000274979
ENST00000402430 ENSP00000385418
ENST00000402530 ENSP00000383985
ENST00000451047 ENSP00000403625
ENST00000475532
ENST00000471606
ENST00000487192
ENST00000481071
ENST00000459928
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005229 intracellular calcium activated chloride channel activity
GO:0017128 phospholipid scramblase activity
Biological Process
GO:0006821 chloride transport
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
GO:0061589 calcium activated phosphatidylserine scrambling
GO:0061590 calcium activated phosphatidylcholine scrambling
GO:0061591 calcium activated galactosylceramide scrambling
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000034107
View Gene Order
Pathways
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_267716
Orphan transporters pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.163909
RefSeq NM_001001666 NM_001001891 XM_006712558
HUGO
OMIM
CCDS CCDS33423 CCDS46563
HPRD 16090
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca