Version 5.4
Homo sapiens Gene: TRERF1
Summary
InnateDB Gene IDBG-87179.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRERF1
Gene Name transcriptional regulating factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124496
Encoded Proteins
IDBP-87181
transcriptional regulating factor 1
IDBP-87183
transcriptional regulating factor 1
IDBP-87185
transcriptional regulating factor 1
IDBP-87187
transcriptional regulating factor 1
IDBP-585252
transcriptional regulating factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:42224931-42452051
Strand Reverse strand
Band p21.1
Transcripts
ENST00000372922 ENSP00000362013
ENST00000354325 ENSP00000346285
ENST00000340840 ENSP00000339438
ENST00000372917 ENSP00000362008
ENST00000541110 ENSP00000439689
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008134 transcription factor binding
GO:0008301 DNA binding, bending
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
GO:0046872 metal ion binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0006694 steroid biosynthetic process
GO:0006707 cholesterol catabolic process
GO:0007275 multicellular organismal development
GO:0042592 homeostatic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046885 regulation of hormone biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000064043
View Gene Order
ENSBTAG00000015321
Not yet available
Cross-References
SwissProt Q96PN7
TrEMBL
UniProt Splice Variant
Entrez Gene 55809
UniGene Hs.485392 Hs.610491
RefSeq XM_006715147 NM_001297573 NM_001297574 NM_033502 XM_005249223 XM_006715143 XM_006715145 XM_006715149
HUGO HGNC:18273
OMIM 610322
CCDS CCDS4867 CCDS75455
HPRD 11647
IMGT
EMBL AF297872 AJ277275 AJ277276 AK002096 AL096814 AM404183 AM404259
GenPept AAL01653 BAA92082 CAB88206 CAB88207 CAD92526 CAD92527 CAD92528 CAL49295 CAL49297
RNA Seq Atlas 55809

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca