Homo sapiens Gene: SLC22A7
Summary
InnateDB Gene IDBG-87931.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC22A7
Gene Name solute carrier family 22 (organic anion transporter), member 7
Synonyms NLT; OAT2
Species Homo sapiens
Ensembl Gene ENSG00000137204
Encoded Proteins
solute carrier family 22 (organic anion transporter), member 7
solute carrier family 22 (organic anion transporter), member 7
solute carrier family 22 (organic anion transporter), member 7
solute carrier family 22 (organic anion transporter), member 7
solute carrier family 22 (organic anion transporter), member 7
solute carrier family 22 (organic anion transporter), member 7
solute carrier family 22 (organic anion transporter), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:43295694-43305538
Strand Forward strand
Band p21.1
Transcripts
ENST00000372585 ENSP00000361666
ENST00000372589 ENSP00000361670
ENST00000372574 ENSP00000361655
ENST00000451757 ENSP00000416052
ENST00000449231 ENSP00000411818
ENST00000436107 ENSP00000393836
ENST00000480882
ENST00000487175
ENST00000498232 ENSP00000434707
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015075 ion transmembrane transporter activity
GO:0015347 sodium-independent organic anion transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0015711 organic anion transport
GO:0034220 ion transmembrane transport
GO:0035634 response to stilbenoid
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Organic anion transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
Organic cation/anion/zwitterion transport pathway
SLC-mediated transmembrane transport pathway
KEGG
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt Q9Y694
TrEMBL
UniProt Splice Variant
Entrez Gene 10864
UniGene Hs.485438
RefSeq NM_006672 XM_006714971 NM_153320 XM_006714970
HUGO HGNC:10971
OMIM 604995
CCDS CCDS4892 CCDS4893
HPRD 05409
IMGT
EMBL AF097518 AF210455 AK290796 AK290806 AL583834 AY050498 BC033805 CH471081 EU562669
GenPept AAD37091 AAG43523 AAH33805 AAL12496 ACB21045 BAF83485 BAF83495 CAI14462 CAI14463 CAI14464 CAI14466 EAX04172 EAX04175
RNA Seq Atlas 10864