Version 5.4
Homo sapiens Gene: FNBP1
Summary
InnateDB Gene IDBG-89354.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FNBP1
Gene Name formin binding protein 1
Synonyms FBP17
Species Homo sapiens
Ensembl Gene ENSG00000187239
Encoded Proteins
IDBP-89360
formin binding protein 1
IDBP-382344
formin binding protein 1
IDBP-382346
formin binding protein 1
IDBP-382353
formin binding protein 1
IDBP-382354
formin binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:129887187-130043194
Strand Reverse strand
Band q34.11
Transcripts
ENST00000355681 ENSP00000347907
ENST00000446176 ENSP00000413625
ENST00000420781 ENSP00000407548
ENST00000443566 ENSP00000389117
ENST00000449089 ENSP00000415602
ENST00000478129
ENST00000462766
ENST00000482107
ENST00000491905
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0042802 identical protein binding
Biological Process
GO:0006412 translation
GO:0006897 endocytosis
GO:0007165 signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005764 lysosome
GO:0005840 ribosome
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0005938 cell cortex
GO:0016023 cytoplasmic membrane-bounded vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000075415
View Gene Order
ENSBTAG00000020313
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.627895
RefSeq NM_015033 XM_005251824 XM_005251825 XM_005251827 XM_005251828 XM_005251829 XM_005251830 XM_005251834 XM_006717017
HUGO
OMIM
CCDS CCDS48040
HPRD 10446
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca