InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Fnbp1

Summary

InnateDB Gene

IDBG-157485.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fnbp1

Gene Name

formin binding protein 1

Synonyms

1110057E06Rik; 2210010H06Rik; FBP1; Fbp17

Species

Mus musculus

Ensembl Gene

ENSMUSG00000075415

Encoded Proteins

IDBP-157487

formin binding protein 1

IDBP-157489

formin binding protein 1

IDBP-157491

formin binding protein 1

IDBP-253618

formin binding protein 1

IDBP-253607

formin binding protein 1

IDBP-253611

formin binding protein 1

IDBP-253615

formin binding protein 1

IDBP-253617

formin binding protein 1

IDBP-253620

formin binding protein 1

IDBP-253624

formin binding protein 1

IDBP-542852

formin binding protein 1

IDBP-542854

formin binding protein 1

IDBP-542855

formin binding protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187239:
The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:31026206-31142008

Strand

Reverse strand

Band

Transcripts

ENSMUST00000075326	ENSMUSP00000074796
ENSMUST00000100208	ENSMUSP00000097782
ENSMUST00000100207	ENSMUSP00000097781
ENSMUST00000073879	ENSMUSP00000109188
ENSMUST00000113564	ENSMUSP00000109194
ENSMUST00000113562	ENSMUSP00000109192
ENSMUST00000113560	ENSMUSP00000109190
ENSMUST00000113559	ENSMUSP00000109189
ENSMUST00000113555	ENSMUSP00000109184
ENSMUST00000113552	ENSMUSP00000109181
ENSMUST00000128500	ENSMUSP00000115013
ENSMUST00000128431
ENSMUST00000138581
ENSMUST00000136181	ENSMUSP00000120580
ENSMUST00000149196	ENSMUSP00000121282
ENSMUST00000136085

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0042802	identical protein binding

Biological Process

GO:0006897	endocytosis
GO:0007165	signal transduction

Cellular Component

GO:0005575	cellular_component
GO:0005764	lysosome
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0005905	coated pit
GO:0005938	cell cortex
GO:0016023	cytoplasmic membrane-bounded vesicle

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000187239

View Gene Order

ENSBTAG00000020313

Not yet available

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.440460 Mm.440993 Mm.488894 Mm.52297

RefSeq

NM_001038700 NM_001177648 NM_001177649 NM_001177650 NM_019406 XM_006497692 XM_006497693 XM_006497694

OMIM

CCDS

CCDS15894 CCDS38097 CCDS50560 CCDS50561 CCDS57165

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas