Homo sapiens Gene: COL16A1
Summary
InnateDB Gene IDBG-95481.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COL16A1
Gene Name collagen, type XVI, alpha 1
Synonyms 447AA
Species Homo sapiens
Ensembl Gene ENSG00000084636
Encoded Proteins
collagen, type XVI, alpha 1
collagen, type XVI, alpha 1
collagen, type XVI, alpha 1
collagen, type XVI, alpha 1
collagen, type XVI, alpha 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:31652247-31704319
Strand Reverse strand
Band p35.2
Transcripts
ENST00000373672 ENSP00000362776
ENST00000373668 ENSP00000362772
ENST00000373667 ENSP00000362771
ENST00000440437 ENSP00000390281
ENST00000458715 ENSP00000411457
ENST00000488897
ENST00000461217
ENST00000488128
ENST00000466829
ENST00000470799
ENST00000482910
ENST00000468459
ENST00000479100
ENST00000474000
ENST00000482478
ENST00000529928
ENST00000532877
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007565 female pregnancy
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0030574 collagen catabolic process
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005597 collagen type XVI
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Integrin cell surface interactions pathway
Collagen biosynthesis and modifying enzymes pathway
Collagen degradation pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
Collagen formation pathway
KEGG
INOH
Integrin signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL H7BY97
UniProt Splice Variant
Entrez Gene 1307
UniGene Hs.368921
RefSeq NM_001856
HUGO HGNC:2193
OMIM 120326
CCDS CCDS41297
HPRD 00381
IMGT
EMBL AC114488
GenPept
RNA Seq Atlas 1307