Version 5.4
Homo sapiens Gene: RNF19B
Summary
InnateDB Gene IDBG-95845.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF19B
Gene Name ring finger protein 19B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116514
Encoded Proteins
IDBP-95847
ring finger protein 19B
IDBP-95849
ring finger protein 19B
IDBP-95851
ring finger protein 19B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary IBRDC3 is a cytolysis-associated transmembrane protein expressed in natural killer (NK) cells and T lymphocytes following cytokine stimulation (Kozlowski et al., 1999 [PubMed 10438909]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:32936445-32964685
Strand Reverse strand
Band p35.1
Transcripts
ENST00000373456 ENSP00000362555
ENST00000235150 ENSP00000235150
ENST00000356990 ENSP00000349482
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0016567 protein ubiquitination
GO:0042267 natural killer cell mediated cytotoxicity
GO:0072643 interferon-gamma secretion
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
GO:0044194 cytolytic granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028793
View Gene Order
ENSBTAG00000008330
Not yet available
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6ZMZ0
TrEMBL
UniProt Splice Variant
Entrez Gene 127544
UniGene Hs.591504 Hs.602585
RefSeq NM_001127361 NM_001300826 NM_153341 XM_005270460 XM_006710356 XM_006710358
HUGO HGNC:26886
OMIM 610872
CCDS CCDS372 CCDS44107 CCDS72754
HPRD
IMGT
EMBL AK074486 AK131439 AL031602 BC020595 BC062374 BC113560 BC143687 CH471059
GenPept AAH20595 AAH62374 AAI13561 AAI43688 BAC11017 BAD18585 EAX07490 EAX07491
RNA Seq Atlas 127544

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca