Homo sapiens Gene: RAET1G
Summary
InnateDB Gene IDBG-97837.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAET1G
Gene Name retinoic acid early transcript 1G
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000203722
Encoded Proteins
retinoic acid early transcript 1G
retinoic acid early transcript 1G
retinoic acid early transcript 1G
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the RAET1 family, such as RAET1G, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E (MIM 609243) and RAET1G differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1; MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. (Radosavljevic et al., 2002 [PubMed 11827464]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:149916878-149923121
Strand Reverse strand
Band q25.1
Transcripts
ENST00000367361 ENSP00000356330
ENST00000367360 ENSP00000356329
ENST00000479265 ENSP00000417503
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0046703 natural killer cell lectin-like receptor binding
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
GO:0042267 natural killer cell mediated cytotoxicity
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031225 anchored component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
Natural killer cell mediated cytotoxicity pathway
INOH
PID NCI
Cross-References
SwissProt Q6H3X3
TrEMBL J7HEM2
UniProt Splice Variant
Entrez Gene 353091
UniGene Hs.558792
RefSeq NM_001001788
HUGO HGNC:16795
OMIM 609244
CCDS CCDS43514
HPRD 16467
IMGT
EMBL AY172579 AY172580 JX162560
GenPept AAO22238 AAO22239 AFP99104
RNA Seq Atlas 353091