Version 5.4
Homo sapiens Gene: SEMA6C
Summary
InnateDB Gene IDBG-102291.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEMA6C
Gene Name sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
Synonyms m-SemaY; m-SemaY2; SEMAY
Species Homo sapiens
Ensembl Gene ENSG00000143434
Encoded Proteins
IDBP-102293
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
IDBP-102295
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
IDBP-102297
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
IDBP-102299
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
IDBP-811834
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
IDBP-811835
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the semaphorin family. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:151131685-151146664
Strand Reverse strand
Band q21.3
Transcripts
ENST00000368914 ENSP00000357910
ENST00000368913 ENSP00000357909
ENST00000368912 ENSP00000357908
ENST00000341697 ENSP00000344148
ENST00000479820
ENST00000464018
ENST00000489944
ENST00000485745
ENST00000613223 ENSP00000482163
ENST00000621728 ENSP00000483227
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007411 axon guidance
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038777
View Gene Order
ENSBTAG00000007281
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.516316 Hs.713961
RefSeq NM_001178061 NM_001178062 NM_030913 XM_005244833 XM_005244835 XM_005244836 XM_005244837 XM_006711120 XM_006711123
HUGO
OMIM
CCDS CCDS53363 CCDS53364 CCDS984
HPRD 10220
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca