Version 5.4
Homo sapiens Gene: SLC25A37
Summary
InnateDB Gene IDBG-12031.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC25A37
Gene Name solute carrier family 25 (mitochondrial iron transporter), member 37
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147454
Encoded Proteins
IDBP-12033
solute carrier family 25, member 37
IDBP-363906
solute carrier family 25, member 37
IDBP-473404
solute carrier family 25, member 37
IDBP-473976
solute carrier family 25, member 37
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009 [PubMed 19805291]).[supplied by OMIM, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:23528805-23575463
Strand Forward strand
Band p21.2
Transcripts
ENST00000290075 ENSP00000290075
ENST00000417331 ENSP00000402782
ENST00000519973 ENSP00000429200
ENST00000518881
ENST00000519192
ENST00000520654
ENST00000523930 ENSP00000428066
ENST00000523883
ENST00000517923
ENST00000520949
ENST00000522164
ENST00000521637
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005381 iron ion transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0034755 iron ion transmembrane transport
GO:0044281 small molecule metabolic process
GO:0048250 mitochondrial iron ion transport
GO:0055072 iron ion homeostasis
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034248
View Gene Order
ENSBTAG00000019099
Not yet available
Pathways
NETPATH
REACTOME
REACT_150353
Mitochondrial iron-sulfur cluster biogenesis pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.122514 Hs.596025 Hs.603062 Hs.603458 Hs.709743 Hs.726050
RefSeq NM_016612 XM_006716352
HUGO
OMIM
CCDS CCDS47828
HPRD 17605
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca