Version 5.4
Mus musculus Gene: Rhob
Summary
InnateDB Gene IDBG-128375.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rhob
Gene Name ras homolog gene family, member B
Synonyms AA017882; Arh6; Arhb
Species Mus musculus
Ensembl Gene ENSMUSG00000054364
Encoded Proteins
IDBP-128377
ras homolog gene family, member B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143878:
Gene Information
Type Protein coding
Genomic Location Chromosome 12:8497763-8499985
Strand Reverse strand
Band A1.1
Transcripts
ENSMUST00000067384 ENSMUSP00000067013
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019003 GDP binding
Biological Process
GO:0000910 cytokinesis
GO:0001525 angiogenesis
GO:0006184 GTP catabolic process
GO:0006927 transformed cell apoptotic process
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0008333 endosome to lysosome transport
GO:0015031 protein transport
GO:0030154 cell differentiation
GO:0043065 positive regulation of apoptotic process
GO:0045766 positive regulation of angiogenesis
GO:0045786 negative regulation of cell cycle
GO:0070301 cellular response to hydrogen peroxide
GO:0071479 cellular response to ionizing radiation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0031902 late endosome membrane
GO:0032154 cleavage furrow
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143878
View Gene Order
ENSBTAG00000046054
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_224553
Hemostasis pathway
REACT_254215
Signaling by GPCR pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_246650
Sema4D induced cell migration and growth-cone collapse pathway
REACT_220092
GPVI-mediated activation cascade pathway
REACT_204733
G alpha (12/13) signalling events pathway
REACT_261444
Axon guidance pathway
REACT_210090
Rho GTPase cycle pathway
REACT_234744
Sema4D in semaphorin signaling pathway
REACT_188576
Developmental Biology pathway
REACT_263034
Semaphorin interactions pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1695
GPVI-mediated activation cascade pathway
REACT_18407
G alpha (12/13) signalling events pathway
REACT_11051
Rho GTPase cycle pathway
REACT_19277
Sema4D induced cell migration and growth-cone collapse pathway
REACT_19259
Sema4D in semaphorin signaling pathway
REACT_111045
Developmental Biology pathway
REACT_19271
Semaphorin interactions pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_14797
Signaling by GPCR pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_18266
Axon guidance pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_604
Hemostasis pathway
REACT_211252
Sema4D in semaphorin signaling pathway
REACT_205369
Signaling by GPCR pathway
REACT_218808
Sema4D induced cell migration and growth-cone collapse pathway
REACT_212196
Hemostasis pathway
REACT_209572
Platelet activation, signaling and aggregation pathway
REACT_211150
Rho GTPase cycle pathway
REACT_214353
Signal Transduction pathway
REACT_219098
GPVI-mediated activation cascade pathway
REACT_209608
Signaling by Rho GTPases pathway
REACT_203140
Axon guidance pathway
REACT_214436
GPCR downstream signaling pathway
REACT_205384
G alpha (12/13) signalling events pathway
REACT_221457
Semaphorin interactions pathway
REACT_220844
Developmental Biology pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P62746
TrEMBL Q4FJM5
UniProt Splice Variant
Entrez Gene 11852
UniGene Mm.411433
RefSeq NM_007483
OMIM
CCDS CCDS25799
HPRD
IMGT
MGI ID MGI:107949
MGI Symbol Rhob
EMBL AF481943 AK013784 AK164518 BC018275 BC110992 CH466582 CT010379 X99963
GenPept AAH18275 AAI10993 AAL89687 BAB28993 BAE37818 CAA68228 CAJ18586 EDK98405
RNA Seq Atlas 11852

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca