Mus musculus Gene: Rpa3
Summary
InnateDB Gene IDBG-128401.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rpa3
Gene Name replication protein A3
Synonyms 14kDa; C330026P08Rik;
Species Mus musculus
Ensembl Gene ENSMUSG00000012483
Encoded Proteins
replication protein A3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106399:
Gene Information
Type Protein coding
Genomic Location Chromosome 6:8255936-8259173
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000012627 ENSMUSP00000012627
ENSMUST00000159594
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0006289 nucleotide-excision repair
GO:0006298 mismatch repair
GO:0006310 DNA recombination
GO:0007346 regulation of mitotic cell cycle
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005654 nucleoplasm
GO:0005662 DNA replication factor A complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Processive synthesis on the lagging strand pathway
Transcription-coupled NER (TC-NER) pathway
Mus musculus biological processes pathway
Removal of the Flap Intermediate pathway
Cell Cycle, Mitotic pathway
Gap-filling DNA repair synthesis and ligation in TC-NER pathway
Meiotic Recombination pathway
Chromosome Maintenance pathway
Synthesis of DNA pathway
DNA strand elongation pathway
Repair synthesis for gap-filling by DNA polymerase in TC-NER pathway
DNA Replication pathway
Dual incision reaction in GG-NER pathway
Cellular responses to stress pathway
Global Genomic NER (GG-NER) pathway
Assembly of the RAD51-ssDNA nucleoprotein complex pathway
Double-Strand Break Repair pathway
Gap-filling DNA repair synthesis and ligation in GG-NER pathway
Homologous DNA pairing and strand exchange pathway
Telomere Maintenance pathway
Processing of DNA double-strand break ends pathway
Formation of incision complex in GG-NER pathway
Cell Cycle pathway
Nucleotide Excision Repair pathway
Cell Cycle Checkpoints pathway
Presynaptic phase of homologous DNA pairing and strand exchange pathway
Removal of the Flap Intermediate from the C-strand pathway
Repair synthesis of patch ~27-30 bases long by DNA polymerase pathway
DNA Repair pathway
Activation of the pre-replicative complex pathway
Telomere C-strand (Lagging Strand) Synthesis pathway
M/G1 Transition pathway
G2/M Checkpoints pathway
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) pathway
Cellular response to heat stress pathway
G1/S Transition pathway
Mitotic G1-G1/S phases pathway
Mismatch Repair pathway
Extension of Telomeres pathway
Activation of ATR in response to replication stress pathway
Processive synthesis on the C-strand of the telomere pathway
Lagging Strand Synthesis pathway
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) pathway
Regulation of HSF1-mediated heat shock response pathway
Meiosis pathway
Meiotic recombination pathway
Homologous Recombination Repair pathway
DNA Replication Pre-Initiation pathway
S Phase pathway
Homologous recombination repair of replication-independent double-strand breaks pathway
KEGG
DNA replication pathway
Nucleotide excision repair pathway
Mismatch repair pathway
Homologous recombination pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
DNA Replication pathway
Cellular responses to stress pathway
Repair synthesis for gap-filling by DNA polymerase in TC-NER pathway
Telomere C-strand (Lagging Strand) Synthesis pathway
Transcription-coupled NER (TC-NER) pathway
Synthesis of DNA pathway
Repair synthesis of patch ~27-30 bases long by DNA polymerase pathway
Removal of the Flap Intermediate from the C-strand pathway
Regulation of HSF1-mediated heat shock response pathway
Homologous Recombination Repair pathway
Removal of the Flap Intermediate pathway
Mitotic G1-G1/S phases pathway
S Phase pathway
Formation of incision complex in GG-NER pathway
Chromosome Maintenance pathway
G2/M Checkpoints pathway
Processing of DNA double-strand break ends pathway
Dual incision reaction in GG-NER pathway
DNA Replication Pre-Initiation pathway
Global Genomic NER (GG-NER) pathway
Telomere Maintenance pathway
G1/S Transition pathway
Double-Strand Break Repair pathway
Activation of the pre-replicative complex pathway
Cell Cycle pathway
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) pathway
Meiotic recombination pathway
Cellular response to heat stress pathway
Processive synthesis on the lagging strand pathway
M/G1 Transition pathway
Homologous DNA pairing and strand exchange pathway
Homologous recombination repair of replication-independent double-strand breaks pathway
Activation of ATR in response to replication stress pathway
Cell Cycle, Mitotic pathway
DNA strand elongation pathway
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) pathway
Mismatch Repair pathway
Processive synthesis on the C-strand of the telomere pathway
Meiosis pathway
HSF1 activation pathway
Extension of Telomeres pathway
Lagging Strand Synthesis pathway
Presynaptic phase of homologous DNA pairing and strand exchange pathway
Nucleotide Excision Repair pathway
Gap-filling DNA repair synthesis and ligation in GG-NER pathway
Gap-filling DNA repair synthesis and ligation in TC-NER pathway
DNA Repair pathway
Assembly of the RAD51-ssDNA nucleoprotein complex pathway
Cell Cycle Checkpoints pathway
KEGG
DNA replication pathway
Nucleotide excision repair pathway
Mismatch repair pathway
Homologous recombination pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_026632
OMIM
CCDS CCDS19909
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas