Version 5.4
Mus musculus Gene: Cadps
Summary
InnateDB Gene IDBG-132306.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cadps
Gene Name Ca2+-dependent secretion activator
Synonyms AU067781; CAPS; CAPS1; mKIAA1121
Species Mus musculus
Ensembl Gene ENSMUSG00000054423
Encoded Proteins
IDBP-132308
Ca2+-dependent secretion activator
IDBP-255541
Ca2+-dependent secretion activator
IDBP-255543
Ca2+-dependent secretion activator
IDBP-718158
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163618:
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:12372563-12823079
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000067491 ENSMUSP00000064706
ENSMUST00000112658 ENSMUSP00000108277
ENSMUST00000112657 ENSMUSP00000108276
ENSMUST00000177814 ENSMUSP00000136076
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0046872 metal ion binding
Biological Process
GO:0015031 protein transport
GO:0016050 vesicle organization
GO:0016082 synaptic vesicle priming
GO:0050432 catecholamine secretion
Cellular Component
GO:0030054 cell junction
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0045202 synapse
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163618
View Gene Order
ENSBTAG00000005321
Not yet available
Cross-References
SwissProt Q80TJ1
TrEMBL J3QJW3 K4DI76
UniProt Splice Variant
Entrez Gene 27062
UniGene Mm.474227
RefSeq NM_001042617 NM_012061 XM_006518025 XM_006518028 XM_006518029 XM_006518031 XM_006518032 XM_006518033 XM_006518034 XM_006518035 XM_006518036
OMIM
CCDS CCDS36806 CCDS36807
HPRD
IMGT
MGI ID MGI:1350922
MGI Symbol Cadps
EMBL AC116395 AC154250 AC154592 AC156025 AK122453 AK161919 BC057065 D86214
GenPept AAH57065 BAA13044 BAC65735 BAE36633
RNA Seq Atlas 27062

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca