Version 5.4
Mus musculus Gene: Mkl2
Summary
InnateDB Gene IDBG-133693.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mkl2
Gene Name MKL/myocardin-like 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000009569
Encoded Proteins
IDBP-133681
MKL/myocardin-like 2
IDBP-133695
MKL/myocardin-like 2
IDBP-248819
MKL/myocardin-like 2
IDBP-535870
MKL/myocardin-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186260:
Gene Information
Type Protein coding
Genomic Location Chromosome 16:13256481-13417529
Strand Forward strand
Band A1
Transcripts
ENSMUST00000056715 ENSMUSP00000054993
ENSMUST00000009713 ENSMUSP00000009713
ENSMUST00000115809 ENSMUSP00000111476
ENSMUST00000149359 ENSMUSP00000122815
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001889 liver development
GO:0003007 heart morphogenesis
GO:0007507 heart development
GO:0010467 gene expression
GO:0010468 regulation of gene expression
GO:0045844 positive regulation of striated muscle tissue development
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048514 blood vessel morphogenesis
GO:0048568 embryonic organ development
GO:0048738 cardiac muscle tissue development
GO:0051145 smooth muscle cell differentiation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186260
View Gene Order
ENSBTAG00000008728
Not yet available
Cross-References
SwissProt
TrEMBL Q8R2L3
UniProt Splice Variant
Entrez Gene 239719
UniGene Mm.270643
RefSeq XM_006522111 NM_001122667 NM_153588 NM_181860 XM_006522108 XM_006522109 XM_006522110
OMIM
CCDS CCDS37257 CCDS37258 CCDS49768
HPRD
IMGT
MGI ID MGI:3050795
MGI Symbol Mkl2
EMBL AC160961 AC163640 BC028459
GenPept AAH28459
RNA Seq Atlas 239719

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca