Version 5.4
Mus musculus Gene: Perp
Summary
InnateDB Gene IDBG-135762.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Perp
Gene Name PERP, TP53 apoptosis effector
Synonyms 1110017A08Rik; KCP1; KRTCAP1; PIGPC1; THW
Species Mus musculus
Ensembl Gene ENSMUSG00000019851
Encoded Proteins
IDBP-135764
PERP, TP53 apoptosis effector
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112378:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:18845071-18857073
Strand Forward strand
Band A3
Transcripts
ENSMUST00000019998 ENSMUSP00000019998
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002934 desmosome organization
GO:0034113 heterotypic cell-cell adhesion
GO:0045862 positive regulation of proteolysis
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097186 amelogenesis
GO:0097202 activation of cysteine-type endopeptidase activity
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0030057 desmosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112378
View Gene Order
ENSBTAG00000020097
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04115
p53 signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04115
p53 signaling pathway pathway
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
deltanp63pathway
Validated transcriptional targets of deltaNp63 isoforms
tap63pathway
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt Q9JK95
TrEMBL
UniProt Splice Variant
Entrez Gene 64058
UniGene Mm.28209 Mm.397381
RefSeq NM_022032
OMIM
CCDS CCDS23714
HPRD
IMGT
MGI ID MGI:1929938
MGI Symbol Perp
EMBL AF249870 AF251009 AK003734 AK009184 AK009190 BC021772
GenPept AAF64306 AAF70261 AAH21772 BAB22968 BAB26126 BAB26130
RNA Seq Atlas 64058

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca