Version 5.4
Homo sapiens Gene: PERP
Summary
InnateDB Gene IDBG-97036.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PERP
Gene Name PERP, TP53 apoptosis effector
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112378
Encoded Proteins
IDBP-387499
PERP, TP53 apoptosis effector
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:138088505-138107511
Strand Reverse strand
Band q23.3
Transcripts
ENST00000421351 ENSP00000397157
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002934 desmosome organization
GO:0034113 heterotypic cell-cell adhesion
GO:0045862 positive regulation of proteolysis
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097186 amelogenesis
GO:0097202 activation of cysteine-type endopeptidase activity
Cellular Component
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0030057 desmosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019851
View Gene Order
ENSBTAG00000020097
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04115
p53 signaling pathway pathway
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
deltanp63pathway
Validated transcriptional targets of deltaNp63 isoforms
tap63pathway
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.201446 Hs.594390
RefSeq NM_022121
HUGO
OMIM
CCDS CCDS5188
HPRD 17836
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca