Homo sapiens Gene: PERP
Summary
InnateDB Gene IDBG-97036.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PERP
Gene Name PERP, TP53 apoptosis effector
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000112378
Encoded Proteins
PERP, TP53 apoptosis effector
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:138088505-138107511
Strand Reverse strand
Band q23.3
Transcripts
ENST00000421351 ENSP00000397157
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002934 desmosome organization
GO:0034113 heterotypic cell-cell adhesion
GO:0045862 positive regulation of proteolysis
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097186 amelogenesis
GO:0097202 activation of cysteine-type endopeptidase activity
Cellular Component
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0030057 desmosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
p53 signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Direct p53 effectors
Validated transcriptional targets of deltaNp63 isoforms
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.201446 Hs.594390
RefSeq NM_022121
HUGO
OMIM
CCDS CCDS5188
HPRD 17836
IMGT
EMBL
GenPept
RNA Seq Atlas