Mus musculus Gene: Wtap
Summary
InnateDB Gene IDBG-137755.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wtap
Gene Name Wilms' tumour 1-associating protein
Synonyms 2810408K05Rik; 9430038B09Rik;
Species Mus musculus
Ensembl Gene ENSMUSG00000060475
Encoded Proteins
Wilms' tumour 1-associating protein
Wilms' tumour 1-associating protein
Wilms' tumour 1-associating protein
Wilms' tumour 1-associating protein
Wilms' tumour 1-associating protein
Wilms' tumour 1-associating protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146457:
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:12966796-12992546
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000007007 ENSMUSP00000007007
ENSMUST00000159551 ENSMUSP00000124205
ENSMUST00000159986 ENSMUSP00000123961
ENSMUST00000160781 ENSMUSP00000124138
ENSMUST00000159104 ENSMUSP00000125337
ENSMUST00000162395 ENSMUSP00000125419
ENSMUST00000161901
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0007049 cell cycle
GO:0007275 multicellular organismal development
GO:0008380 RNA splicing
GO:0080009 mRNA methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0016607 nuclear speck
GO:0031965 nuclear membrane
GO:0036396 MIS complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL F7CCI4
UniProt Splice Variant
Entrez Gene 60532
UniGene Mm.275521 Mm.309476 Mm.397359 Mm.490351
RefSeq NM_001113532 NM_001113533 NM_175394 XM_006523341
OMIM
CCDS CCDS49949 CCDS49950
HPRD
IMGT
MGI ID MGI:1926395
MGI Symbol Wtap
EMBL AL589878
GenPept
RNA Seq Atlas 60532