Version 5.4
Homo sapiens Gene: WTAP
Summary
InnateDB Gene IDBG-98560.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WTAP
Gene Name Wilms tumor 1 associated protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146457
Encoded Proteins
IDBP-98562
Wilms tumor 1 associated protein
IDBP-98566
Wilms tumor 1 associated protein
IDBP-810486
Wilms tumor 1 associated protein
IDBP-810487
Wilms tumor 1 associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:159725585-159756319
Strand Forward strand
Band q25.3
Transcripts
ENST00000358372 ENSP00000351141
ENST00000337387 ENSP00000336911
ENST00000494513
ENST00000462110
ENST00000614346 ENSP00000484404
ENST00000621533 ENSP00000479438
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 15 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0007049 cell cycle
GO:0008380 RNA splicing
GO:0080009 mRNA methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016607 nuclear speck
GO:0031965 nuclear membrane
GO:0036396 MIS complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060475
View Gene Order
ENSBTAG00000007974
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001270531 NM_001270532 NM_001270533 NM_004906 NM_152857 NM_152858
HUGO
OMIM
CCDS CCDS5266 CCDS5267 CCDS75542
HPRD 09259
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca