InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: SNRPD1

Summary

InnateDB Gene

IDBG-1426.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNRPD1

Gene Name

small nuclear ribonucleoprotein D1 polypeptide 16kDa

Synonyms

HsT2456; Sm-D1; SMD1; SNRPD

Species

Homo sapiens

Ensembl Gene

ENSG00000167088

Encoded Proteins

IDBP-1428

small nuclear ribonucleoprotein D1 polypeptide 16kDa

IDBP-726394

IDBP-727441

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. [provided by RefSeq, Jul 2008]
This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:21612267-21630456

Strand

Forward strand

Band

q11.2

Transcripts

ENST00000300413	ENSP00000300413
ENST00000579618	ENSP00000463676
ENST00000582475	ENSP00000463568

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 136 experimentally validated interaction(s) in this database.

Experimentally validated
Total	136 [view]
Protein-Protein	135 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000245	spliceosomal complex assembly
GO:0000387	spliceosomal snRNP assembly
GO:0000398	mRNA splicing, via spliceosome
GO:0008380	RNA splicing
GO:0010467	gene expression
GO:0016070	RNA metabolic process
GO:0034660	ncRNA metabolic process

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005685	U1 snRNP
GO:0005687	U4 snRNP
GO:0005689	U12-type spliceosomal complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0030532	small nuclear ribonucleoprotein complex
GO:0034709	methylosome
GO:0034715	pICln-Sm protein complex
GO:0034719	SMN-Sm protein complex
GO:0071013	catalytic step 2 spliceosome

Orthologs

Species

Mus musculus

Gene ID

Gene Order

ENSMUSG00000002477

View Gene Order

Pathways

NETPATH

REACTOME

REACT_11066

snRNP Assembly pathway

REACT_467

mRNA Splicing - Major Pathway pathway

REACT_1753

mRNA Splicing - Minor Pathway pathway

REACT_125

Processing of Capped Intron-Containing Pre-mRNA pathway

REACT_11052

Metabolism of non-coding RNA pathway

REACT_1735

mRNA Splicing pathway

REACT_71

Gene Expression pathway

KEGG

hsa05322

Systemic lupus erythematosus pathway

hsa03040

Spliceosome pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Hs.464734 Hs.597957 Hs.723796

RefSeq

NM_006938

HUGO

OMIM

CCDS

CCDS32801

HPRD

03040

IMGT

EMBL

GenPept

RNA Seq Atlas