Mus musculus Gene: Enox2
Summary
InnateDB Gene IDBG-144224.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Enox2
Gene Name ecto-NOX disulfide-thiol exchanger 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031109
Encoded Proteins
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165675:
The protein encoded by this gene is a growth-related cell surface protein. It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The two activities alternate with a period length of about 24 minutes. The encoded protein also displays prion-like properties. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome X:49009707-49288259
Strand Reverse strand
Band A5
Transcripts
ENSMUST00000033437 ENSMUSP00000033437
ENSMUST00000114918 ENSMUSP00000110568
ENSMUST00000114914 ENSMUSP00000110564
ENSMUST00000114912 ENSMUSP00000110562
ENSMUST00000114911 ENSMUSP00000110561
ENSMUST00000155770
ENSMUST00000137518
ENSMUST00000141393
ENSMUST00000167659 ENSMUSP00000128885
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0015035 protein disulfide oxidoreductase activity
Biological Process
GO:0007624 ultradian rhythm
GO:0040008 regulation of growth
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005615 extracellular space
GO:0009897 external side of plasma membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.327730 Mm.398131
RefSeq NM_001271447 NM_001271448 NM_001271449 NM_001271450 NM_001271451 NM_145951 XM_006541472 XM_006541473 XM_006541474
OMIM
CCDS CCDS30115 CCDS72377 CCDS72378
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas