Version 5.4
| Mus musculus Gene: Enox2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-144224.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Enox2 | ||||||||
| Gene Name | ecto-NOX disulfide-thiol exchanger 2 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000031109 | ||||||||
| Encoded Proteins |
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
ecto-NOX disulfide-thiol exchanger 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165675:
The protein encoded by this gene is a growth-related cell surface protein. It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The two activities alternate with a period length of about 24 minutes. The encoded protein also displays prion-like properties. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome X:49009707-49288259 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | A5 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
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Gene ID
Gene Order
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| Cross-References | |||||||||
| SwissProt | Q8R0Z2 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 209224 | ||||||||
| UniGene | Mm.327730 Mm.398131 | ||||||||
| RefSeq | NM_145951 NM_001271447 NM_001271448 NM_001271449 NM_001271450 NM_001271451 XM_006541472 XM_006541473 XM_006541474 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS30115 CCDS72377 CCDS72378 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:2384799 | ||||||||
| MGI Symbol | Enox2 | ||||||||
| EMBL | AK034058 AK041822 BC025915 BC026450 BX294194 | ||||||||
| GenPept | AAH25915 AAH26450 BAC28565 BAC31077 CAM21582 | ||||||||
| RNA Seq Atlas | 209224 | ||||||||