Version 5.4
Mus musculus Gene: Prpf4b
Summary
InnateDB Gene IDBG-144277.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prpf4b
Gene Name PRP4 pre-mRNA processing factor 4 homolog B (yeast)
Synonyms 2610037H07; cbp143; Prp4; Prp4k; Prpk
Species Mus musculus
Ensembl Gene ENSMUSG00000021413
Encoded Proteins
IDBP-144281
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112739:
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:34875494-34902877
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000077853 ENSMUSP00000077019
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0006468 protein phosphorylation
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112739
View Gene Order
ENSBTAG00000002086
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
NetPath_11
TCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q61136
TrEMBL C7G3P2 Q8BPG8 Q8C5G1
UniProt Splice Variant
Entrez Gene 19134
UniGene Mm.10027 Mm.417570
RefSeq NM_013830
OMIM
CCDS CCDS26448
HPRD
IMGT
MGI ID MGI:109584
MGI Symbol Prpf4b
EMBL AB516304 AF033663 AF283466 AK020579 AK021274 AK076020 AK078611 AK083926 BC141272 BC141273 CH466546 U48737
GenPept AAB03269 AAC32042 AAI41273 AAI41274 AAM19102 BAB32137 BAB32358 BAC36125 BAC37340 BAC39069 BAI22793 EDL40895
RNA Seq Atlas 19134

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca