Version 5.4
Mus musculus Gene: Gnl3
Summary
InnateDB Gene IDBG-144362.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gnl3
Gene Name guanine nucleotide binding protein-like 3 (nucleolar)
Synonyms Ns
Species Mus musculus
Ensembl Gene ENSMUSG00000042354
Encoded Proteins
IDBP-144364
guanine nucleotide binding protein-like 3 (nucleolar)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163938:
The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:31012434-31019089
Strand Reverse strand
Band B
Transcripts
ENSMUST00000037739 ENSMUSP00000047119
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 62 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 62 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006184 GTP catabolic process
GO:0008283 cell proliferation
GO:0042127 regulation of cell proliferation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163938
View Gene Order
ENSBTAG00000014549
Not yet available
Cross-References
SwissProt Q8CI11
TrEMBL
UniProt Splice Variant
Entrez Gene 30877
UniGene Mm.88512
RefSeq NM_153547
OMIM
CCDS CCDS26905
HPRD
IMGT
MGI ID MGI:1353651
MGI Symbol Gnl3
EMBL AK077523 AY181025 AY185498 BC037996
GenPept AAH37996 AAO19472 AAO19473 BAC36844
RNA Seq Atlas 30877

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca