Mus musculus Gene: Cdc40
Summary
InnateDB Gene IDBG-146000.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdc40
Gene Name cell division cycle 40
Synonyms 1200003H23Rik; EHB3; PRP17;
Species Mus musculus
Ensembl Gene ENSMUSG00000038446
Encoded Proteins
cell division cycle 40 homolog (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168438:
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:40831626-40883143
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000044166 ENSMUSP00000044305
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
mRNA 3'-end processing pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
RNA Polymerase II Transcription Termination pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
KEGG
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
mRNA 3'-end processing pathway
RNA Polymerase II Transcription Termination pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
KEGG
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9DC48
TrEMBL
UniProt Splice Variant
Entrez Gene 71713
UniGene Mm.46063
RefSeq NM_027879
OMIM
CCDS CCDS48546
HPRD
IMGT
MGI ID MGI:1918963
MGI Symbol Cdc40
EMBL AK004569 BC147503 BC158078
GenPept AAI47504 AAI58079 BAB23380
RNA Seq Atlas 71713