Mus musculus Gene: Mgat4a
Summary
InnateDB Gene IDBG-146044.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mgat4a
Gene Name mannoside acetylglucosaminyltransferase 4, isoenzyme A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000026110
Encoded Proteins
mannoside acetylglucosaminyltransferase 4, isoenzyme A
mannoside acetylglucosaminyltransferase 4, isoenzyme A
mannoside acetylglucosaminyltransferase 4, isoenzyme A
mannoside acetylglucosaminyltransferase 4, isoenzyme A
mannoside acetylglucosaminyltransferase 4, isoenzyme A
mannoside acetylglucosaminyltransferase 4, isoenzyme A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000071073:
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:37439340-37541016
Strand Reverse strand
Band B
Transcripts
ENSMUST00000042161 ENSMUSP00000038894
ENSMUST00000151952 ENSMUSP00000114175
ENSMUST00000154819 ENSMUSP00000121181
ENSMUST00000143636 ENSMUSP00000122909
ENSMUST00000149791 ENSMUSP00000115778
ENSMUST00000148047 ENSMUSP00000118692
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006486 protein glycosylation
Cellular Component
GO:0000139 Golgi membrane
GO:0005576 extracellular region
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
N-Glycan antennae elongation pathway
N-glycan antennae elongation in the medial/trans-Golgi pathway
Transport to the Golgi and subsequent modification pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
KEGG
N-Glycan biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Post-translational protein modification pathway
N-Glycan antennae elongation pathway
N-glycan antennae elongation in the medial/trans-Golgi pathway
Asparagine N-linked glycosylation pathway
Metabolism of proteins pathway
Transport to the Golgi and subsequent modification pathway
KEGG
N-Glycan biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.25861 Mm.443123
RefSeq NM_001290801 NM_173870 XM_006496022 XM_006496023 XM_006496024 XM_006496025 XM_006496026 XM_006496027
OMIM
CCDS CCDS14893 CCDS69882
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas