Mus musculus Gene: Irf2bp1
Summary
InnateDB Gene IDBG-149056.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Irf2bp1
Gene Name interferon regulatory factor 2 binding protein 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000044030
Encoded Proteins
interferon regulatory factor 2 binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Homo sapiens] IRF2BP1 is a transcriptional co-repressor of IRF2 and, through physically association, enhances JDP2 polyubiquitination. IRF2BP1 has also been shown to repress ATF2-mediated transcriptional activation from a CRE-containing promoter.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170604:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:19004065-19006761
Strand Forward strand
Band A3
Transcripts
ENSMUST00000053713 ENSMUSP00000061234
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8R3Y8
TrEMBL
UniProt Splice Variant
Entrez Gene 272359
UniGene Mm.274237 Mm.401546
RefSeq NM_178757
OMIM
CCDS CCDS20885
HPRD
IMGT
MGI ID MGI:2442159
MGI Symbol Irf2bp1
EMBL AK031834 AK087457 BC019164 BC036162
GenPept AAH19164 AAH36162 BAC27572 BAC39883
RNA Seq Atlas 272359