Homo sapiens Gene: IRF2BP1
Summary
InnateDB Gene IDBG-58309.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IRF2BP1
Gene Name interferon regulatory factor 2 binding protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170604
Encoded Proteins
interferon regulatory factor 2 binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
IRF2BP1 is a transcriptional co-repressor of IRF2 and, through physically association, enhances JDP2 polyubiquitination. IRF2BP1 has also been shown to repress ATF2-mediated transcriptional activation from a CRE-containing promoter.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:45883607-45886170
Strand Reverse strand
Band q13.32
Transcripts
ENST00000302165 ENSP00000307265
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8IU81
TrEMBL
UniProt Splice Variant
Entrez Gene 26145
UniGene Hs.515477
RefSeq NM_015649
HUGO HGNC:21728
OMIM 615331
CCDS CCDS12678
HPRD
IMGT
EMBL AK223622 AL080159 AY278022 BC005834 BC038222 BC039002 BC078181 CH471126
GenPept AAH05834 AAH38222 AAH39002 AAH78181 AAP78943 BAD97342 CAB45750 EAW57396
RNA Seq Atlas 26145