Version 5.4
Homo sapiens Gene: GSPT1
Summary
InnateDB Gene IDBG-15002.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GSPT1
Gene Name G1 to S phase transition 1
Synonyms 551G9.2; eRF3a; ETF3A; GST1
Species Homo sapiens
Ensembl Gene ENSG00000103342
Encoded Proteins
IDBP-368745
G1 to S phase transition 1
IDBP-368746
G1 to S phase transition 1
IDBP-368747
G1 to S phase transition 1
IDBP-750317
IDBP-753589
IDBP-746908
IDBP-749655
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:11868128-11916082
Strand Reverse strand
Band p13.13
Transcripts
ENST00000420576 ENSP00000399539
ENST00000434724 ENSP00000398131
ENST00000439887 ENSP00000408399
ENST00000562169 ENSP00000454538
ENST00000567631
ENST00000563468 ENSP00000454351
ENST00000565267 ENSP00000456057
ENST00000562794
ENST00000568849 ENSP00000456897
ENST00000564790
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 37 [view]
Protein-Protein 36 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003747 translation release factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006184 GTP catabolic process
GO:0006415 translational termination
GO:0006479 protein methylation
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000062203
View Gene Order
ENSBTAG00000003577
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.528780 Hs.653493 Hs.694140 Hs.712597
RefSeq NM_001130006 NM_001130007 NM_002094 XM_005255274 XM_005255275
HUGO
OMIM
CCDS CCDS45412 CCDS45413 CCDS45414
HPRD 00753
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca