Version 5.4
Mus musculus Gene: Ippk
Summary
InnateDB Gene IDBG-150798.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ippk
Gene Name inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Synonyms 1810043M15Rik; InsP6
Species Mus musculus
Ensembl Gene ENSMUSG00000021385
Encoded Proteins
IDBP-150800
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127080:
The protein encoded by this gene is a kinase that phosphorylates position 2 of inositol-1,3,4,5,6-pentakisphosphate to form inositol-1,2,3,4,5,6-hexakisphosphate (InsP6). InsP6 has a variety of functions, including stimulation of DNA repair, endocytosis, and mRNA export. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:49421311-49462990
Strand Forward strand
Band A5
Transcripts
ENSMUST00000021817 ENSMUSP00000021817
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0035299 inositol pentakisphosphate 2-kinase activity
Biological Process
GO:0052746 inositol phosphorylation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000127080
View Gene Order
ENSBTAG00000011859
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_196480
Synthesis of IPs in the nucleus pathway
REACT_196482
Synthesis of pyrophosphates in the cytosol pathway
REACT_196476
Inositol phosphate metabolism pathway
KEGG
mmu04070
Phosphatidylinositol signaling system pathway
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150188
Synthesis of pyrophosphates in the cytosol pathway
REACT_150275
Synthesis of IPs in the nucleus pathway
REACT_150154
Inositol phosphate metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
INOH
PID NCI
Cross-References
SwissProt Q6P1C1
TrEMBL Q05CK0
UniProt Splice Variant
Entrez Gene 75678
UniGene Mm.390586
RefSeq NM_001276399 NM_199056
OMIM
CCDS CCDS26500
HPRD
IMGT
MGI ID MGI:1922928
MGI Symbol Ippk
EMBL AK029085 AK160092 AK167467 BC024630 BC062167 BC065157
GenPept AAH24630 AAH62167 AAH65157 BAE20447 BAE35623 BAE39551
RNA Seq Atlas 75678

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca