Homo sapiens Gene: ZMIZ2
Summary
InnateDB Gene IDBG-15128.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZMIZ2
Gene Name zinc finger, MIZ-type containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000122515
Encoded Proteins
zinc finger, MIZ-type containing 2
zinc finger, MIZ-type containing 2
zinc finger, MIZ-type containing 2
zinc finger, MIZ-type containing 2
zinc finger, MIZ-type containing 2
zinc finger, MIZ-type containing 2
zinc finger, MIZ-type containing 2
zinc finger, MIZ-type containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:44748581-44769881
Strand Forward strand
Band p13
Transcripts
ENST00000309315 ENSP00000311778
ENST00000265346 ENSP00000265346
ENST00000413916 ENSP00000409648
ENST00000457123 ENSP00000415501
ENST00000416856 ENSP00000406820
ENST00000441627 ENSP00000414723
ENST00000433667 ENSP00000396601
ENST00000492001
ENST00000478045
ENST00000463056
ENST00000480964
ENST00000492558
ENST00000463931
ENST00000482322
ENST00000615423 ENSP00000483853
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0043596 nuclear replication fork
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Regulation of Androgen receptor activity
Cross-References
SwissProt Q8NF64
TrEMBL B3KR25 C9JDA5
UniProt Splice Variant
Entrez Gene 83637
UniGene Hs.77978
RefSeq NM_031449 NM_001300959 NM_174929 XM_005249873 XM_005249869 XM_005249874 XM_005249872
HUGO HGNC:22229
OMIM 611196
CCDS CCDS43576 CCDS75591 CCDS43577
HPRD 13225
IMGT
EMBL AB015330 AB067473 AC004859 AC013436 AK090415 AK090841 AL136572 AL831933 AY426594 BC021924 BC110435 CH236960 CH471128
GenPept AAH21924 AAI10436 AAP22368 AAR85526 BAA34789 BAB67779 BAC03396 BAG52237 CAB66507 CAH56269 EAL23750 EAW61083 EAW61084 EAW61085
RNA Seq Atlas 83637