Mus musculus Gene: Nlrp5
InnateDB Gene IDBG-153886.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nlrp5
Gene Name NLR family, pyrin domain containing 5
Synonyms Mater; Nalp5; Op1; PAN11
Species Mus musculus
Ensembl Gene ENSMUSG00000015721
Encoded Proteins
NLR family, pyrin domain containing 5
NLR family, pyrin domain containing 5
NLR family, pyrin domain containing 5
NLR family, pyrin domain containing 5
NLR family, pyrin domain containing 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
[Homo sapiens] NLRP5 is a part of the NLRP (Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containing) family, has a role in apoptosis and inflammation.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171487:
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:23385889-23441922
Strand Forward strand
Band A3
ENSMUST00000086341 ENSMUSP00000083524
ENSMUST00000015866 ENSMUSP00000015866
ENSMUST00000108441 ENSMUSP00000104080
ENSMUST00000139661 ENSMUSP00000118638
ENSMUST00000133237 ENSMUSP00000122007
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0001701 in utero embryonic development
GO:0007566 embryo implantation
GO:0009566 fertilization
GO:0009887 organ morphogenesis
GO:0031647 regulation of protein stability
GO:0034613 cellular protein localization
GO:0043487 regulation of RNA stability
GO:0043623 cellular protein complex assembly
GO:0070997 neuron death
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005938 cell cortex
GO:0043234 protein complex
GO:0045179 apical cortex
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt Q9R1M5
UniProt Splice Variant
Entrez Gene 23968
UniGene Mm.333653 Mm.420946
RefSeq NM_011860 NM_001039143
CCDS CCDS20930 CCDS20929
MGI ID MGI:1345193
MGI Symbol Nlrp5
EMBL AF074018 AF143559 AF143560 AF143561 AF143562 AF143563 AF143564 AF143565 AF143566 AF143567 AF143568 AF143569 AF143570 AF143571 AF143572 AF143573 AK135731 AY196361 AY196362 AY329484 AY329485 AY329486 AY329487 AY329488 AY329489 AY329490 AY329491 BC053384
GenPept AAD51762 AAF64393 AAH53384 AAO52697 AAO52698 AAQ94607 AAQ94608 AAQ94609 AAQ94610 AAQ94611 AAQ94612 AAQ94613 AAQ94614 BAE22633
RNA Seq Atlas 23968