Mus musculus Gene: Gpaa1
Summary
InnateDB Gene IDBG-154605.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpaa1
Gene Name GPI anchor attachment protein 1
Synonyms C80044; mGAA1
Species Mus musculus
Ensembl Gene ENSMUSG00000022561
Encoded Proteins
GPI anchor attachment protein 1
GPI anchor attachment protein 1
GPI anchor attachment protein 1
GPI anchor attachment protein 1
GPI anchor attachment protein 1
GPI anchor attachment protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197858:
Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:76331231-76334907
Strand Forward strand
Band D3
Transcripts
ENSMUST00000023221 ENSMUSP00000023221
ENSMUST00000164972 ENSMUSP00000127108
ENSMUST00000172281 ENSMUSP00000132986
ENSMUST00000163798
ENSMUST00000169378 ENSMUSP00000128507
ENSMUST00000170121 ENSMUSP00000133173
ENSMUST00000164680
ENSMUST00000168948 ENSMUSP00000126326
ENSMUST00000171005
ENSMUST00000165179
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003923 GPI-anchor transamidase activity
GO:0005515 protein binding
GO:0034235 GPI anchor binding
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042765 GPI-anchor transamidase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Attachment of GPI anchor to uPAR pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Attachment of GPI anchor to uPAR pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6T7Y8
UniProt Splice Variant
Entrez Gene 14731
UniGene Mm.5903
RefSeq NM_010331 XM_006520446
OMIM
CCDS CCDS37120
HPRD
IMGT
MGI ID MGI:1202392
MGI Symbol Gpaa1
EMBL AC155074
GenPept
RNA Seq Atlas 14731