InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Thy1

Summary

InnateDB Gene

IDBG-155394.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Thy1

Gene Name

thymus cell antigen 1, theta

Synonyms

CD90; T25; Thy-1; Thy-1.2; Thy1.1; Thy1.2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000032011

Encoded Proteins

IDBP-250925

thymus cell antigen 1, theta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154096:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:44043384-44048579

Strand

Forward strand

Band

A5.1

Transcripts

ENSMUST00000114840

ENSMUSP00000110489

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005100	Rho GTPase activator activity
GO:0005178	integrin binding
GO:0005515	protein binding
GO:0019899	enzyme binding
GO:0019901	protein kinase binding
GO:0034235	GPI anchor binding

Biological Process

GO:0001525	angiogenesis
GO:0006469	negative regulation of protein kinase activity
GO:0007010	cytoskeleton organization
GO:0016337	single organismal cell-cell adhesion
GO:0030336	negative regulation of cell migration
GO:0032321	positive regulation of Rho GTPase activity
GO:0043547	positive regulation of GTPase activity
GO:0046549	retinal cone cell development
GO:0048041	focal adhesion assembly
GO:0050771	negative regulation of axonogenesis
GO:0050852	T cell receptor signaling pathway
GO:0050860	negative regulation of T cell receptor signaling pathway
GO:0050870	positive regulation of T cell activation
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016324	apical plasma membrane
GO:0030425	dendrite
GO:0030426	growth cone
GO:0031362	anchored component of external side of plasma membrane
GO:0045121	membrane raft
GO:0046658	anchored component of plasma membrane
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000154096

View Gene Order

ENSBTAG00000019627

Not yet available

Pathways

NETPATH

REACTOME

KEGG

mmu04670

Leukocyte transendothelial migration pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

hsa04670

Leukocyte transendothelial migration pathway

INOH

PID NCI

integrin2_pathway

Beta2 integrin cell surface interactions

il4_2pathway

IL4-mediated signaling events

integrin3_pathway

Beta3 integrin cell surface interactions

amb2_neutrophils_pathway

amb2 Integrin signaling

Cross-References

SwissProt

P01831

TrEMBL

UniProt Splice Variant

Entrez Gene

21838

UniGene

Mm.3951

RefSeq

NM_009382

OMIM

CCDS

CCDS23093

HPRD

IMGT

MGI ID

MGI:98747

MGI Symbol

Thy1

EMBL

BC054436 M10246 M11160 M12379 X02771 X02772 X02773 X03151

GenPept

AAA40440 AAA40441 AAA40443 AAH54436 CAA26548 CAA26549 CAA26550 CAA26930

RNA Seq Atlas

21838