Homo sapiens Gene: THY1
Summary
InnateDB Gene IDBG-74502.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THY1
Gene Name Thy-1 cell surface antigen
Synonyms CD90;
Species Homo sapiens
Ensembl Gene ENSG00000154096
Encoded Proteins
Thy-1 cell surface antigen
Thy-1 cell surface antigen
Thy-1 cell surface antigen
Thy-1 cell surface antigen
Thy-1 cell surface antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:119417378-119424985
Strand Reverse strand
Band q23.3
Transcripts
ENST00000284240 ENSP00000284240
ENST00000528522 ENSP00000431301
ENST00000528295 ENSP00000432051
ENST00000527590
ENST00000524970 ENSP00000432808
ENST00000524659 ENSP00000435753
ENST00000532974
ENST00000533840
ENST00000580275 ENSP00000464248
ENST00000584021
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0034235 GPI anchor binding
Biological Process
GO:0001525 angiogenesis
GO:0006469 negative regulation of protein kinase activity
GO:0007010 cytoskeleton organization
GO:0016337 single organismal cell-cell adhesion
GO:0030336 negative regulation of cell migration
GO:0032321 positive regulation of Rho GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0046549 retinal cone cell development
GO:0048041 focal adhesion assembly
GO:0050771 negative regulation of axonogenesis
GO:0050852 T cell receptor signaling pathway
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050870 positive regulation of T cell activation
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016324 apical plasma membrane
GO:0030425 dendrite
GO:0030426 growth cone
GO:0031362 anchored component of external side of plasma membrane
GO:0045121 membrane raft
GO:0046658 anchored component of plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Leukocyte transendothelial migration pathway
INOH
PID BIOCARTA
PID NCI
Beta2 integrin cell surface interactions
IL4-mediated signaling events
Beta3 integrin cell surface interactions
amb2 Integrin signaling
Cross-References
SwissProt
TrEMBL E9PIM6
UniProt Splice Variant
Entrez Gene 7070
UniGene Hs.743230
RefSeq NM_006288
HUGO HGNC:11801
OMIM 188230
CCDS CCDS8424
HPRD 11283
IMGT
EMBL AP003396
GenPept
RNA Seq Atlas 7070