Version 5.4
Bos taurus Gene: THY1
Summary
InnateDB Gene IDBG-631960.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THY1
Gene Name thy-1 membrane glycoprotein precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019627
Encoded Proteins
IDBP-683541
thy-1 membrane glycoprotein precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154096:
Gene Information
Type Protein coding
Genomic Location Chromosome 15:30509504-30515399
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026146 ENSBTAP00000026146
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005178 integrin binding
GO:0005515 protein binding
GO:0034235 GPI anchor binding
Biological Process
GO:0001525 angiogenesis
GO:0006469 negative regulation of protein kinase activity
GO:0007010 cytoskeleton organization
GO:0016337 single organismal cell-cell adhesion
GO:0030336 negative regulation of cell migration
GO:0032321 positive regulation of Rho GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0046549 retinal cone cell development
GO:0048041 focal adhesion assembly
GO:0050771 negative regulation of axonogenesis
GO:0050852 T cell receptor signaling pathway
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050870 positive regulation of T cell activation
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016324 apical plasma membrane
GO:0030425 dendrite
GO:0030426 growth cone
GO:0031362 anchored component of external side of plasma membrane
GO:0045121 membrane raft
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000154096
View Gene Order
ENSMUSG00000032011
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04670
Leukocyte transendothelial migration pathway
mmu04670
Leukocyte transendothelial migration pathway
INOH
PID NCI
integrin2_pathway
Beta2 integrin cell surface interactions
il4_2pathway
IL4-mediated signaling events
integrin3_pathway
Beta3 integrin cell surface interactions
amb2_neutrophils_pathway
amb2 Integrin signaling
Cross-References
SwissProt
TrEMBL Q3SX33
UniProt Splice Variant
Entrez Gene 614712
UniGene Bt.53255
RefSeq NM_001034765
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC104530 DAAA02040498
GenPept AAI04531
RNA Seq Atlas 614712

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca