Homo sapiens Gene: ST3GAL5 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-59513.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | ST3GAL5 | ||||||||||
Gene Name | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | ||||||||||
Synonyms | SATI; SIAT9; SIATGM3S; ST3GalV | ||||||||||
Species | Homo sapiens | ||||||||||
Ensembl Gene | ENSG00000115525 | ||||||||||
Encoded Proteins |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 2:85839144-85889014 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | p11.2 | ||||||||||
Transcripts | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||
NETPATH | |||||||||||
REACTOME |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
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KEGG |
Glycosphingolipid biosynthesis pathway
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INOH | |||||||||||
PID NCI | |||||||||||
Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | |||||||||||
UniGene | Hs.736775 | ||||||||||
RefSeq | NM_001042437 NM_003896 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | CCDS1986 CCDS42705 | ||||||||||
HPRD | 05098 | ||||||||||
IMGT | |||||||||||
EMBL | |||||||||||
GenPept | |||||||||||
RNA Seq Atlas | |||||||||||