Mus musculus Gene: Afap1
Summary
InnateDB Gene IDBG-157728.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Afap1
Gene Name actin filament associated protein 1
Synonyms 2600003E23Rik; 9630044L16Rik; Afap; AI848729; mKIAA3018;
Species Mus musculus
Ensembl Gene ENSMUSG00000029094
Encoded Proteins
actin filament associated protein 1
actin filament associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196526:
The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:35893319-36003923
Strand Forward strand
Band B3
Transcripts
ENSMUST00000064571 ENSMUSP00000067779
ENSMUST00000146300
ENSMUST00000141824 ENSMUSP00000119364
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0017124 SH3 domain binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005925 focal adhesion
GO:0015629 actin cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.125167 Mm.411853 Mm.473806
RefSeq NM_027373 XM_006504099
OMIM
CCDS CCDS19236
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas