Version 5.4
Mus musculus Gene: Minpp1
Summary
InnateDB Gene IDBG-158643.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Minpp1
Gene Name multiple inositol polyphosphate histidine phosphatase 1
Synonyms AA408516
Species Mus musculus
Ensembl Gene ENSMUSG00000024896
Encoded Proteins
IDBP-158645
multiple inositol polyphosphate histidine phosphatase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107789:
This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:32485769-32515370
Strand Forward strand
Band C1
Transcripts
ENSMUST00000025827 ENSMUSP00000025827
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003993 acid phosphatase activity
GO:0016791 phosphatase activity
GO:0034417 bisphosphoglycerate 3-phosphatase activity
GO:0052826 inositol hexakisphosphate 2-phosphatase activity
Biological Process
GO:0016311 dephosphorylation
Cellular Component
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000107789
View Gene Order
ENSBTAG00000005928
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_196484
Synthesis of IPs in the ER lumen pathway
REACT_196476
Inositol phosphate metabolism pathway
KEGG
mmu00010
Glycolysis / Gluconeogenesis pathway
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150253
Synthesis of IPs in the ER lumen pathway
REACT_150154
Inositol phosphate metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q9Z2L6
TrEMBL
UniProt Splice Variant
Entrez Gene 17330
UniGene Mm.255116 Mm.296143 Mm.398664
RefSeq NM_010799
OMIM
CCDS CCDS29751
HPRD
IMGT
MGI ID MGI:1336159
MGI Symbol Minpp1
EMBL AB041574 AF046908 AK151486 BC021437
GenPept AAD02434 AAH21437 BAA95058 BAE30439
RNA Seq Atlas 17330

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca