InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cyp2f2

Summary

InnateDB Gene

IDBG-159851.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cyp2f2

Gene Name

cytochrome P450, family 2, subfamily f, polypeptide 2

Synonyms

Cyp2f

Species

Mus musculus

Ensembl Gene

ENSMUSG00000052974

Encoded Proteins

IDBP-159853

cytochrome P450, family 2, subfamily f, polypeptide 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197446:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:27119909-27133660

Strand

Forward strand

Band

Transcripts

ENSMUST00000003100	ENSMUSP00000003100
ENSMUST00000133841

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0005506	iron ion binding
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019825	oxygen binding
GO:0020037	heme binding

Biological Process

GO:0009636	response to toxic substance
GO:0018931	naphthalene metabolic process
GO:0018979	trichloroethylene metabolic process
GO:0055114	oxidation-reduction process