Version 5.4
Mus musculus Gene: Prmt5
Summary
InnateDB Gene IDBG-161405.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prmt5
Gene Name protein arginine N-methyltransferase 5
Synonyms Jbp1; Skb1
Species Mus musculus
Ensembl Gene ENSMUSG00000023110
Encoded Proteins
IDBP-161407
protein arginine N-methyltransferase 5
IDBP-541115
protein arginine N-methyltransferase 5
IDBP-787788
protein arginine N-methyltransferase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100462:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:54507187-54517525
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000023873 ENSMUSP00000023873
ENSMUST00000139964 ENSMUSP00000121502
ENSMUST00000132227 ENSMUSP00000138549
ENSMUST00000147214
ENSMUST00000133552
ENSMUST00000138367
ENSMUST00000132801
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 89 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 28 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 89 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008469 histone-arginine N-methyltransferase activity
GO:0035243 protein-arginine omega-N symmetric methyltransferase activity
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000387 spliceosomal snRNP assembly
GO:0006351 transcription, DNA-templated
GO:0006479 protein methylation
GO:0018216 peptidyl-arginine methylation
GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0034969 histone arginine methylation
GO:0035246 peptidyl-arginine N-methylation
GO:0042118 endothelial cell activation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0034709 methylosome
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100462
View Gene Order
ENSBTAG00000010890
Not yet available
Pathways
NETPATH
REACTOME
REACT_218274
Chromatin organization pathway
REACT_224866
Metabolism of non-coding RNA pathway
REACT_202766
Chromatin modifying enzymes pathway
REACT_206812
snRNP Assembly pathway
REACT_233572
Gene Expression pathway
REACT_244207
RMTs methylate histone arginines pathway
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11066
snRNP Assembly pathway
REACT_11052
Metabolism of non-coding RNA pathway
REACT_172623
Chromatin organization pathway
REACT_228108
RMTs methylate histone arginines pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_71
Gene Expression pathway
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
hdac_classi_pathway
Signaling events mediated by HDAC Class I
p53regulationpathway
p53 pathway
e2f_pathway
E2F transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.196585
RefSeq NM_013768 XM_006519073 XM_006519074
OMIM
CCDS CCDS27091
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca