Mus musculus Gene: Pacsin2
Summary
InnateDB Gene IDBG-168133.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pacsin2
Gene Name protein kinase C and casein kinase substrate in neurons 2
Synonyms AI197433;
Species Mus musculus
Ensembl Gene ENSMUSG00000016664
Encoded Proteins
protein kinase C and casein kinase substrate in neurons 2
protein kinase C and casein kinase substrate in neurons 2
protein kinase C and casein kinase substrate in neurons 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100266:
This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:83375607-83464606
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000056177 ENSMUSP00000058320
ENSMUST00000171436 ENSMUSP00000131504
ENSMUST00000165095 ENSMUSP00000130098
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0008289 lipid binding
GO:0042802 identical protein binding
GO:0070300 phosphatidic acid binding
Biological Process
GO:0007165 signal transduction
GO:0030036 actin cytoskeleton organization
GO:0036010 protein localization to endosome
GO:0045806 negative regulation of endocytosis
GO:0048858 cell projection morphogenesis
GO:0070836 caveola assembly
GO:0072584 caveolin-mediated endocytosis
GO:0097320 membrane tubulation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005901 caveola
GO:0005911 cell-cell junction
GO:0019898 extrinsic component of membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0032587 ruffle membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0055038 recycling endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
Adp-ribosylation factor [Biocarta view]
Rho cell motility signaling pathway [Biocarta view]
Rac1 cell motility signaling pathway [Biocarta view]
T cell receptor signaling pathway [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.23978
RefSeq NM_001159509 NM_001159510 NM_011862 XM_006520979 XM_006520980 XM_006520981 XM_006520982 XM_006520983
OMIM
CCDS CCDS27701
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas