Version 5.4
Mus musculus Gene: Smc1b
Summary
InnateDB Gene IDBG-170290.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smc1b
Gene Name structural maintenance of chromosomes 1B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022432
Encoded Proteins
IDBP-170292
structural maintenance of chromosomes 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000077935:
SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:85064691-85131957
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000023068 ENSMUSP00000023068
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0007062 sister chromatid cohesion
GO:0007126 meiotic nuclear division
GO:0051276 chromosome organization
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000794 condensed nuclear chromosome
GO:0000795 synaptonemal complex
GO:0000800 lateral element
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0030893 meiotic cohesin complex
GO:0034991 nuclear meiotic cohesin complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000077935
View Gene Order
ENSBTAG00000024132
Not yet available
Pathways
NETPATH
REACTOME
REACT_75800
Meiotic Synapsis pathway
REACT_200794
Mus musculus biological processes pathway
REACT_198626
Meiotic synapsis pathway
REACT_188804
Cell Cycle pathway
REACT_198624
Meiosis pathway
KEGG
mmu04110
Cell cycle pathway
mmu04114
Oocyte meiosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75792
Meiotic synapsis pathway
REACT_115566
Cell Cycle pathway
REACT_111183
Meiosis pathway
KEGG
hsa04110
Cell cycle pathway
hsa04114
Oocyte meiosis pathway
INOH
PID NCI
Cross-References
SwissProt Q920F6
TrEMBL A1L2Z0
UniProt Splice Variant
Entrez Gene 140557
UniGene Mm.182737
RefSeq NM_080470 XM_006520411
OMIM
CCDS CCDS27718
HPRD
IMGT
MGI ID MGI:2154049
MGI Symbol Smc1b
EMBL AF303827 BC129800 CH466550
GenPept AAI29801 AAL09333 EDL04440
RNA Seq Atlas 140557

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca