Version 5.4
Mus musculus Gene: Obsl1
Summary
InnateDB Gene IDBG-171498.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Obsl1
Gene Name obscurin-like 1
Synonyms AW822216
Species Mus musculus
Ensembl Gene ENSMUSG00000026211
Encoded Proteins
IDBP-253603
obscurin-like 1
IDBP-253605
obscurin-like 1
IDBP-536227
obscurin-like 1
IDBP-537323
obscurin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124006:
Cytoskeletal adaptor proteins function in linking the internal cytoskeleton of cells to the cell membrane. This gene encodes a cytoskeletal adaptor protein, which is a member of the Unc-89/obscurin family. The protein contains multiple N- and C-terminal immunoglobulin (Ig)-like domains and a central fibronectin type 3 domain. Mutations in this gene cause 3M syndrome type 2. Alternatively spliced transcript variants encoding different isoforms have been found in this gene. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:75479310-75506452
Strand Reverse strand
Band C4
Transcripts
ENSMUST00000113567 ENSMUSP00000109197
ENSMUST00000113565 ENSMUSP00000109195
ENSMUST00000156499
ENSMUST00000154636
ENSMUST00000156705
ENSMUST00000155084 ENSMUSP00000114553
ENSMUST00000132252 ENSMUSP00000117420
ENSMUST00000145382
ENSMUST00000150293
ENSMUST00000138352
ENSMUST00000127507
ENSMUST00000145306
ENSMUST00000129403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0007030 Golgi organization
GO:0007088 regulation of mitosis
GO:0034067 protein localization to Golgi apparatus
GO:0050775 positive regulation of dendrite morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:1990393 3M complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000124006
View Gene Order
ENSBTAG00000040338
Not yet available
Cross-References
SwissProt
TrEMBL D3YYU8
UniProt Splice Variant
Entrez Gene 98733
UniGene Mm.236454 Mm.443861
RefSeq NM_178884 XM_006496585 XM_006496586
OMIM
CCDS CCDS15077
HPRD
IMGT
MGI ID MGI:2138628
MGI Symbol Obsl1
EMBL AC115011
GenPept
RNA Seq Atlas 98733

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca