Version 5.4
Mus musculus Gene: March7
Summary
InnateDB Gene IDBG-172914.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol March7
Gene Name membrane-associated ring finger (C3HC4) 7
Synonyms Axo; Axot; Gtrgeo17
Species Mus musculus
Ensembl Gene ENSMUSG00000026977
Encoded Proteins
IDBP-172916
membrane-associated ring finger (C3HC4) 7
IDBP-172918
membrane-associated ring finger (C3HC4) 7
IDBP-172920
membrane-associated ring finger (C3HC4) 7
IDBP-537995
membrane-associated ring finger (C3HC4) 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136536:
MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:60209887-60250676
Strand Forward strand
Band C1.1
Transcripts
ENSMUST00000102748 ENSMUSP00000099809
ENSMUST00000102747 ENSMUSP00000099808
ENSMUST00000067542 ENSMUSP00000068961
ENSMUST00000143806
ENSMUST00000131813
ENSMUST00000142485 ENSMUSP00000116925
ENSMUST00000134905
ENSMUST00000126986
ENSMUST00000136367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136536
View Gene Order
ENSBTAG00000008755
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.260635 Mm.410136
RefSeq NM_020575 XM_006499949 XM_006499952
OMIM
CCDS CCDS16057
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca