Version 5.4
Mus musculus Gene: Mark3
Summary
InnateDB Gene IDBG-173285.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mark3
Gene Name MAP/microtubule affinity-regulating kinase 3
Synonyms 1600015G02Rik; A430080F22Rik; C-TAK1; Emk2; ETK-1; ETK1; MPK10
Species Mus musculus
Ensembl Gene ENSMUSG00000007411
Encoded Proteins
IDBP-173289
MAP/microtubule affinity-regulating kinase 3
IDBP-173291
MAP/microtubule affinity-regulating kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000075413:
The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:111574510-111656227
Strand Forward strand
Band F1
Transcripts
ENSMUST00000084953 ENSMUSP00000082017
ENSMUST00000075281 ENSMUSP00000074757
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 42 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000075413
View Gene Order
ENSBTAG00000013410
Not yet available
Cross-References
SwissProt Q03141
TrEMBL Q91Y96 Q9CW99
UniProt Splice Variant
Entrez Gene 17169
UniGene
RefSeq NM_021516 NM_022801 XM_006515522
OMIM
CCDS CCDS26181 CCDS26182
HPRD
IMGT
MGI ID MGI:1341865
MGI Symbol Mark3
EMBL AF240783 AH011175 AK002654 AK075742 AK132247 AK166157 BC026445 X57244
GenPept AAF64456 AAH26445 AAL18865 BAB22261 BAC35922 BAE21056 BAE38602 CAA40520
RNA Seq Atlas 17169

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca