Version 5.4
Mus musculus Gene: Nt5c2
Summary
InnateDB Gene IDBG-173710.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nt5c2
Gene Name 5'-nucleotidase, cytosolic II
Synonyms 2010002I23Rik; cN-II; CnII; ENSMUSG00000025039; Gm9751; Gmp; Nt5b; Pnt5
Species Mus musculus
Ensembl Gene ENSMUSG00000025041
Encoded Proteins
IDBP-173712
5'-nucleotidase, cytosolic II
IDBP-622069
5'-nucleotidase, cytosolic II
IDBP-622074
5'-nucleotidase, cytosolic II
IDBP-622077
5'-nucleotidase, cytosolic II
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000076685:
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5\'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:46886831-47015153
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000086961 ENSMUSP00000084180
ENSMUST00000172239 ENSMUSP00000130898
ENSMUST00000174731 ENSMUSP00000134590
ENSMUST00000168536 ENSMUSP00000129126
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0008253 5'-nucleotidase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0016311 dephosphorylation
GO:0046040 IMP metabolic process
GO:0046085 adenosine metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000076685
View Gene Order
ENSBTAG00000012858
Not yet available
Pathways
NETPATH
REACTOME
REACT_263730
Purine metabolism pathway
REACT_188937
Metabolism pathway
REACT_196553
Abacavir metabolism pathway
REACT_196556
Abacavir transport and metabolism pathway
REACT_245662
Metabolism of nucleotides pathway
REACT_253802
Purine catabolism pathway
KEGG
mmu00760
Nicotinate and nicotinamide metabolism pathway
mmu00240
Pyrimidine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121388
Abacavir metabolism pathway
REACT_2086
Purine catabolism pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_121189
Abacavir transport and metabolism pathway
REACT_111217
Metabolism pathway
REACT_210940
Metabolism of nucleotides pathway
REACT_205922
Purine metabolism pathway
REACT_217054
Abacavir transport and metabolism pathway
REACT_222543
Abacavir metabolism pathway
REACT_219139
Metabolism pathway
REACT_214112
Purine catabolism pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00760
Nicotinate and nicotinamide metabolism pathway
hsa00230
Purine metabolism pathway
INOH
INOH website
Nicotinate Nicotinamide metabolism pathway
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.40965 Mm.473499
RefSeq NM_001164363 NM_001164365 NM_029810 XM_006527458 XM_006527459 XM_006527460 XM_006527461
OMIM
CCDS CCDS29883 CCDS50461 CCDS50462
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca