Version 5.4
Mus musculus Gene: Rexo1
Summary
InnateDB Gene IDBG-174534.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rexo1
Gene Name REX1, RNA exonuclease 1 homolog (S. cerevisiae)
Synonyms 1700021P10Rik; 2610511M11Rik; AW050347; EloA-BP1; Tceb3bp1
Species Mus musculus
Ensembl Gene ENSMUSG00000047417
Encoded Proteins
IDBP-174536
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
IDBP-788292
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
IDBP-788295
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
IDBP-788296
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000079313:
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:80540922-80561560
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000057910 ENSMUSP00000049705
ENSMUST00000182682
ENSMUST00000182260 ENSMUSP00000138493
ENSMUST00000183233
ENSMUST00000182604
ENSMUST00000183160 ENSMUSP00000138616
ENSMUST00000183073 ENSMUSP00000138329
ENSMUST00000183139
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
Biological Process
GO:0008150 biological_process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000079313
View Gene Order
ENSBTAG00000020232
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 66932
UniGene
RefSeq NM_025852
OMIM
CCDS CCDS24025
HPRD
IMGT
MGI ID MGI:1914182
MGI Symbol Rexo1
EMBL
GenPept
RNA Seq Atlas 66932

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca