Mus musculus Gene: Esco2
Summary
InnateDB Gene IDBG-174583.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Esco2
Gene Name establishment of cohesion 1 homolog 2 (S. cerevisiae)
Synonyms 2410004I17Rik; D030072L07Rik;
Species Mus musculus
Ensembl Gene ENSMUSG00000022034
Encoded Proteins
establishment of cohesion 1 homolog 2 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171320:
This gene encodes a protein that may have acetyltransferase activity and may be required for the establishment of sister chromatid cohesion during the S phase of mitosis. Mutations in this gene have been associated with Roberts syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:65819038-65833994
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000022613 ENSMUSP00000022613
ENSMUST00000136920
ENSMUST00000131729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004468 lysine N-acetyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006275 regulation of DNA replication
GO:0006302 double-strand break repair
GO:0007049 cell cycle
GO:0007059 chromosome segregation
GO:0034421 post-translational protein acetylation
GO:0071168 protein localization to chromatin
Cellular Component
GO:0000785 chromatin
GO:0001741 XY body
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0010369 chromocenter
GO:0031618 nuclear centromeric heterochromatin
GO:0035861 site of double-strand break
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Cell Cycle, Mitotic pathway
Cell Cycle pathway
Establishment of Sister Chromatid Cohesion pathway
S Phase pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
S Phase pathway
Cell Cycle pathway
Cell Cycle, Mitotic pathway
Establishment of Sister Chromatid Cohesion pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8CIB9
TrEMBL
UniProt Splice Variant
Entrez Gene 71988
UniGene
RefSeq NM_028039
OMIM
CCDS CCDS27216
HPRD
IMGT
MGI ID MGI:1919238
MGI Symbol Esco2
EMBL AK010391 AK050845 AK144685 BC033303 BC071275
GenPept AAH33303 AAH71275 BAB26905 BAC34431 BAE26012
RNA Seq Atlas 71988