Version 5.4
Mus musculus Gene: Esco2
Summary
InnateDB Gene IDBG-174583.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Esco2
Gene Name establishment of cohesion 1 homolog 2 (S. cerevisiae)
Synonyms 2410004I17Rik; D030072L07Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000022034
Encoded Proteins
IDBP-174585
establishment of cohesion 1 homolog 2 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171320:
This gene encodes a protein that may have acetyltransferase activity and may be required for the establishment of sister chromatid cohesion during the S phase of mitosis. Mutations in this gene have been associated with Roberts syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:65819038-65833994
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000022613 ENSMUSP00000022613
ENSMUST00000136920
ENSMUST00000131729
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004468 lysine N-acetyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006275 regulation of DNA replication
GO:0006302 double-strand break repair
GO:0007049 cell cycle
GO:0007059 chromosome segregation
GO:0034421 post-translational protein acetylation
GO:0071168 protein localization to chromatin
Cellular Component
GO:0000785 chromatin
GO:0001741 XY body
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0010369 chromocenter
GO:0031618 nuclear centromeric heterochromatin
GO:0035861 site of double-strand break
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171320
View Gene Order
ENSBTAG00000006551
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_188804
Cell Cycle pathway
REACT_196614
Establishment of Sister Chromatid Cohesion pathway
REACT_253623
S Phase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150266
Establishment of Sister Chromatid Cohesion pathway
REACT_899
S Phase pathway
REACT_115566
Cell Cycle pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_028039
OMIM
CCDS CCDS27216
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca