Version 5.4
Homo sapiens Gene: WHSC1L1
Summary
InnateDB Gene IDBG-17572.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WHSC1L1
Gene Name Wolf-Hirschhorn syndrome candidate 1-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147548
Encoded Proteins
IDBP-17574
Wolf-Hirschhorn syndrome candidate 1-like 1
IDBP-17580
Wolf-Hirschhorn syndrome candidate 1-like 1
IDBP-367220
Wolf-Hirschhorn syndrome candidate 1-like 1
IDBP-597027
Wolf-Hirschhorn syndrome candidate 1-like 1
IDBP-584116
Wolf-Hirschhorn syndrome candidate 1-like 1
IDBP-592784
Wolf-Hirschhorn syndrome candidate 1-like 1
IDBP-584390
Wolf-Hirschhorn syndrome candidate 1-like 1
IDBP-587521
Wolf-Hirschhorn syndrome candidate 1-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:38269697-38382272
Strand Reverse strand
Band p11.23
Transcripts
ENST00000317025 ENSP00000313983
ENST00000316985 ENSP00000313410
ENST00000433384 ENSP00000393284
ENST00000528828
ENST00000527502 ENSP00000434730
ENST00000526050
ENST00000528304
ENST00000525081
ENST00000528627 ENSP00000435073
ENST00000529223 ENSP00000435422
ENST00000534155 ENSP00000432544
ENST00000534539 ENSP00000431598
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 36 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0018024 histone-lysine N-methyltransferase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016571 histone methylation
GO:0034968 histone lysine methylation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054823
View Gene Order
ENSBTAG00000001529
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00310
Lysine degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.608111 Hs.722308
RefSeq NM_017778 NM_023034
HUGO
OMIM
CCDS CCDS43729 CCDS6105
HPRD 06155
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca